DR SIMON NGIGI MBUGUA :: :: STAFF EPORTAL - THE TECHNICAL UNIVERSITY OF KENYA

Dr SIMON NGIGI MBUGUA

Lecturer, DEPARTMENT OF CHEMISTRY AND MATERIALS SCIENCE

Applied Sciences and Technology CHEMISTRY AND MATERIAL SCIENCE GEOCHEMISTRY AND ENVIRONMENTAL CHEMISTRY

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Official email

simon.mbugua@tukenya.ac.ke

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Office telephone

+254(020) 2219929, 3341639, 3343672

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Consultation hours

8AM-5PM MON - FRI

About

Dr SIMON NGIGI MBUGUA is a Lecturer, DEPARTMENT OF CHEMISTRY AND MATERIALS SCIENCE at the Technical University of Kenya, specialising in Chemistry, Environmental Chemistry. Dr SIMON NGIGI MBUGUA holds a Doctor of Philosophy (PhD) and is based in the Faculty of Applied Sciences and Technology. Member of: THE ROYAL SOCIETY OF CHEMISTRY, NATIONAL ENVIRONMENT MANAGEMENT AUTHORITY.

Level	Qualification Name	Institution	Year
Doctor of Philosophy (PhD)	CHEMISTRY	UNIVERSITY OF NAIROBI(Kenya)	2020
Masters of Science (M.Sc.)	ENVIRONMENTAL CHEMISTRY	UNIVERSITY OF NAIROBI(Kenya)	2014
Bachelor of Science (BSc)	CHEMISTRY	UNIVERSITY OF NAIROBI(Kenya)	2000

My interests are in sustainable development, coming up with ideas and products capable of finding applications in providing real solutions to problems facing society; photocatalytic degradation of pollutants in water, nanoparticles, study of organometallic compounds for anticancer applications, structural and computational medicinal chemistry.

Title	Link to publication	Year
Mbugua Simon Ngigi, Nyawade Eunice Adhiambo; Photoactivation in Chemotherapeutic Compounds for Cancer Treatment: Opportunities beyond Photodynamic Therapy. Bioinorganic Chemistry and Applications, Wiley 2026.	View online	2026
B. O. Obita, S. N. Mbugua, C. I. Muhanji, and J. O. Lalah, Synthesis and Evaluation of Ceramic-Anchored Cu-Ce-MnOx Catalyst for Low Temperature Reduction of Diesel Engine NOx Emissions Using Liquefied Petroleum Gas or Adblue as Reductants, Energy Science & Engineering (2026): 1-13	View online	2026
NJENGA, L., Mbugua, S., Odhiambo, R., & Onani, M. O. (2023). Addressing the Gaps in Homeostatic Mechanisms of Copper and Copper Dithiocarbamate Complexes in Cancer Therapy: A Shift from Classical Platinum-drugs Mechanisms. Dalton Transactions, 2023, 52, 5823–5847.	View online	2023
Obita, Brian; Mbugua, Simon Ngigi; Muhanji, Clare I.; Lalah, Joseph O.: Selective Catalytic Reduction Techniques for Post-Combustion Control of Nitrogen Oxides Emissions from a Diesel Engine" Journal of Chemistry, Wiley 2026.	View online	2026
Simon N. Mbugua, Nicole R. S. Sibuyi, Lydia W. Njenga, Ruth A Odhiambo Shem O. Wandiga, Mervin Meyer, Roger A. Lalancette, Martin O. Onani, (2020). New Palladium II and Platinum II Complexes based on Pyrrole Schiff Bases: Synthesis, Characterization, X-Ray Structure and Anticancer Activity. American Chemical Society ACS-Omega.	View online	2020
Mbugua Simon Ngigi, (2023). “Fluorescent Chemo sensor nano-materials for Cancer bio-markers signalling: Towards development of non-invasive early detection strategies”, Dyes and Pigments, Elsevier 2023, 111603, ISSN 0143-7208	View online	2023
Mbugua, S.N., (2022). Targeting Tumor Microenvironment by Metal Peroxide Nanoparticles in Cancer Therapy. Wiley. Bioinorganic Chemistry and Applications, Vol. 2022.	View online	2022
Mbugua, S.N., Njenga, L.W., Odhiambo, R.A., Wandiga, S.O. and Onani, M.O., (2021). COVID-19 and Cancer Therapy: Interrelationships and Management of Cancer Cases in the Era of COVID-19. Wiley. Journal of Chemistry, 2021.	View online	2021
Mbugua, S.N., Njenga, L.W., Odhiambo, R.A., Wandiga, S.O., Onani, M.O. (2020). Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers. Current Topics in Medicinal Chemistry. Bentham Science Publishers.	View online	2020
Simon N. Mbugua, Nicole R. S. Sibuyi, Lydia W. Njenga, Ruth A Odhiambo Shem O. Wandiga, Mervin Meyer, Roger A. Lalancette, Martin O. Onani, (2020). Synthesis, Characterization and DNA Binding Kinetics of New Pd (II) and Pt (II) Thiosemicarbazone Complexes. Spectral, Structural and Anticancer Evaluation. Hindawi Journal of Chemistry Volume 2020	View online	2020
Wandiga S.O., Mbugua S.N., Macharia J.W., Otieno M.A. (2016). Challenges and Solutions to Water Problems in Africa. Book Chapter in ‘Chemistry and Water’ B978-0-12-809330-6.00006-4. Elsevier. 2016.	View online	2016
Wandiga S.O., Kamau G.N., Mbugua S.N., (2017). Titanium (IV) Oxide-Tungsten (VI) Oxide Composite Nanoparticles has photocatalytic potential to degrade selected heavy metals and pesticide pollutants in water. International Journal of Photocatalysis. Photon 121 pp.235-245.	View online	2017
Recent advances in organic fluorescent dyes and responsive materials: from molecular design to functional biomedical applications. J. Mater. Chem. B (2026) 14 (37): 11424–11459.	View online	2026

Name	Project Title	Period
3. John Kamau Nduati (SCP311-2680/2024)-JKUAT	Palladium (II) Salicylidene- Complexes: Synthesis, Characterization, Molecular Docking and Anticancer Activity Studies.	2025-date
2. Edith Chepchirchir (SPCX/06064P/2022)- TUK	Theoretical Investigation of Structure, Molecular Docking, Molecular Dynamic Simulation and Anti-Cancer Activity of Schiff Base Derivatives.	2025-date
1. Brian O. Obita (TUK)- Graduated.	Synthesis and Evaluation of Ceramic-Anchored Copper-Cerium-Manganese Oxide Catalyst for the Reduction of Diesel Engine NO x Emissions Using Liquefied Petroleum Gas as Reductant.	2024-2026

Name	Description	Period
Advanced Chromatography	MSc course on Advanced chromatographic techniques	2023 - TO-DATE
Computational Medicinal Chemistry	MSc course on CADD, molecular modelling, structure based drug design, ligand based drug design, virtual screening, homology modelling, molecular docking, molecular dynamics simulations, ADMET	2023 - TO-DATE
Advanced Bioinorganic Chemistry	MSc course on metal ions and their interactions with biological ligands and the important chemical properties they impart.	2023 - TO-DATE
Pharmaceutical Unit Operations	Unit operations in the pharmaceutical industry; granulation, milling, tabletting, centrifugation, filtration etc	2023 - TO-DATE
Organometallic Chemistry	Organometallic compounds and their industrial applications; synthetic routes, catalysis etc	2023 - TO-DATE

Title	Institution
MEMBER	THE ROYAL SOCIETY OF CHEMISTRY
LEAD EXPERT	NATIONAL ENVIRONMENT MANAGEMENT AUTHORITY

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